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EBV Assay Kits

EBV Assay Kits

Epstein-Barr Virus (EBV) test kits are intended for the diagnosis of EBV-associated diseases, such as infectious mononucleosis, chronic active EBV infection, EBV-related lymphoproliferative disorders and nasopharyngeal carcinoma. The tests can also contribute to laboratory examination of immune deficiency syndromes, chronic fatigue syndrome and other conditions in which reactivation of latent EBV infection is common. These kits are available with multiple markers of EBV infection:

  • Viral capsid antigen (VCA) - structural protein or protein complex; the compound of the viral capsid. 

  • EB-viral nuclear antigen 1 (EBNA-1) - nonstructural nuclear protein, present in latently infected cells

  • Early antigen (EA) - nonstructural protein or protein complex, synthetized in early phase of viral replication cycle. Based on the structure and localization in the infected cells, two components of EA can be distinguished: EA-R (restricted) component is present in distinct regions of cytoplasm, and methanol-sensitive EA-D (diffuse) component is dispersed both in the cytoplasm and in the nucleus.

The antibody response against VCA, EA and EBNA-1 in the course of the EBV infection display different dynamics. The different phases of EBV infection can be distinguished according to the characteristic pattern of IgG, IgM and IgA antibodies against VCA, EBNA-1 and/or EA.

See below for an overview of the EBV kits. If the product you are looking for is not listed, please contact us.

Cat# Product Marker Method Evaluation Tests Samples Sensitivity / Specificity
ODZ-084 IgG (CSF) VCA ELISA quantitative 96 serum, cerebrospinal fluid 98.1% / 97.1%
ODZ-175 IgG and avidity IgG VCA ELISA semiquantitative 48 serum -
ODZ-005 IgM VCA ELISA semiquantitative 96 serum 94.7% / 96.1%
ODZ-096 IgA VCA ELISA semiquantitative 96 serum 85.3% (96%+) / 100%
ODZ-015 IgG – doublestrips ENBA-1 ELISA semiquantitative 96 serum 94.7% / 95.6%
ODZ-001 IgG ENBA-1 ELISA quantitative 96 serum 94.7% / 96.5%
ODZ-002 IgM ENBA-1 ELISA semiquantitative 96 serum 95.5% / 95.5%