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SelfMag Magnetic Delivery System

SA10000 - SelfMag-Amino Kit

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Starting at: $1,157.00

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With the SelfMag Amino Transfection Kit, based on Magnetofection Technology, you can create your own magnetic delivery system! Each kit contains magnetic amino-functionalized nanoparticles, coupling, washing and storage buffers, an EDC coupling reagent, a MagID magnetic device for buffer exchange and washing steps, a MagFectin delivery reagent, and an 8 x 12 cm magnetic plate. This kit has been successfully tested to deliver different types of molecules inside cells such as proteins, enzymes, peptides, and small molecules. With the SelfMag Transfection kit, the molecule of interest is covalently coupled using the surface reactive amino groups of the magnetic nanoparticles. The resulting coupled magnetic nanoparticles are delivered intracellularly with a unique MagFectin reagent.

Figure 1: Coupling of a molecule (L) onto SelfMag amino beads. Depending on the chemical nature of the molecule of interest, coupling onto SelfMag amino beads can be performed using various cross-linkers :carboxyl-containing molecules can be attached using N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC, included in the Kit) ; sulfhydryl-containing molecules can be linked via a N-succinimidyl-3-(2-pyridyldithio)propionate cross-linker (SPDP, not included), and aldehyde-containing molecules can be attached by reductive amination using sodium cyanoborohydride (NaBH3CN, not included).



Figure 2: The MagID - Magnetic Isolation Device is made from an injection molded plastic housing incorporating a high-energy neodymium magnet. It is designed to accommodate standard 1.5 ml tubes and is also suitable for some 2 ml tubes. In this kit, it is used for buffer exchange and washing steps.



Figure 3: The magnetic plate included in this kit has optimized characteristics for magnetofection. It measures 8 x 12 cm. 

Features

  • Suitable for the delivery of biologically active molecules
  • Mono dispersed and size-controlled magnetic nanoparticles
  • Includes ready to use coupling, washing and storage buffers
  • Includes Highly efficient MagFectin delivery reagent
  • Easy handling and fast results
  • Magnetic plate included

Applications

  • In vitro delivery of biomolecules

Contents

  • SelfMag Amino nanoparticles, 1ml
  • Coupling buffer A1, 15ml
  • Washing/storage buffer A2, 15ml
  • EDC reagent, 100mg
  • MagID device
  • MagFectin, 1ml
  • Magnetic plate, 8 x 12 cm