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Magnetic Silica Beads with Carboxyl Surface

Magnetic Silica Beads with Carboxyl Surface

Magnetic silica beads are surface activated magnetic particles intended for covalent immobilization of proteins (e.g. antibodies, enzymes), peptides, nucleic acids or other molecules of interest. Different surface modifications and bead sizes allow for the selection of the optimal product for the application and molecule to be coupled. 

Magnetic silica beads with a carboxyl modified surface are intended for carbodiimide coupling chemistry with NH2 containing molecules. These beads come in three different diameters: 600nm, 1µm and 3µm. Beads of 600nm have a larger surface area, and the sedimentation time of 600nm beads is approximately 4 times slower than that of 1µm beads. This allows longer incubation times without shaking/mixing. Magnetic silica beads with a diameter of 3µm have stronger magnetic properties and will separate approximately 4 times faster than 600nm beads under the same conditions. 

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