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In Vivo Magnetofection

IV-KC30220 - In vivo DogtorMag Starter Kit

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Starting at: $479.00

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This kit includes in vivo DogtorMag Transfection Reagent, in vivo CombiMag Transfection Reagent, and a magnet set. In vivo DogtorMag™ Transfection Reagent is designed for in vivo targeted transfection of various types of nucleic acids such as DNA, RNA, and oligonucleotides using magnetic nanoparticles coated with synthetic lipids. In vivo CombiMag enhances the performance of transfection reagents.

Targeted delivery minimizes systemic distribution, decreases gene vectors inactivation and reduces toxicity. The use of magnetic forces enhances the uptake of magnetic nanoparticles by the target tissue, improving the efficiency of transfection and decreasing the required process time of delivery to only a few minutes. In vivo DogtorMag is suitable for all types of nucleic acid DNA complexes. It can be easily administrated through both systemic administration, such as intravenous and intra-artery injection, and local administration, such as intratumoral, intracerebroventricular, intraperitoneal, intramuscular and subcutaneous injection.


Figure 1: The magnet set includes 1 extra small cylinder magnet (2mm diameter), 1 small cylinder magnet (5mm diameter), 1 cylinder magnet (10mm diameter) and 1 square magnet (18 x 18mm).

Features

  • Increases transfection efficiency
  • Targeted, magnetically-driven process 
  • Reduces required vector doses and systemic dissemination
  • Can be used under non-permissive conditions such as hypothermia and physiological flow conditions
  • Minimizes toxicity
  • Can be applied through systemic administration or local administration
  • Can be used with all types of nucleic acids
  • Magnets are included

Applications

  • In vivo targeted transfection of nucleic acids

Contents

  • In vivo DogtorMag™ Transfection Reagent, 500 µl
  • In vivo CombiMag Transfection Reagent, 500 µl
  • Magnet set - 1 extra small cylinder (2mm diameter), 1 small cylinder (5mm diameter), 1 cylinder (10mm diameter) and 1 square (18 x 18mm)