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Magnetic Silica Beads with Protein A / Protein G

MD10011 - Magnetic Silica Beads coated with Protein A, 600nm, 1ml

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This product is part of Mobitec’s series of M-Beads Magnetic silica beads. M-Beads Magnetic silica beads are designed for separation, concentration and purification of biomolecules, specific cells or cell compartments. They are ideally suited as a solid phase in assay kits. Due to a fast and flexible production process, these beads have unrestricted customization possibilities for sizes, kinetics, optical, surface and binding properties. Magnetic silica beads are available in a variety of sizes, with larger sizes available on request. 

MD10011 has a surface coated with Protein A, a bead size of 600nm, and a concentration of 10mg/ml.  Magnetic silica beads coated with protein A can be used to detect or isolate target proteins by coupling the Fc domain of an IgG antibody to a target protein.  They are ideal for lgG purification and immunoprecipitation. Other applications include capture of immunoglobulins, purification purposes, antibody screening, protein interaction studies, phage display, immunoassays, and cell isolation. 


Protein A and Protein G bind to Fc regions of immunoglobulins. After binding onto magnetic beads with a coating protein A or Protein G, immobilized immunoglobulins can be used for immunoprecipitation of various biomolecules, or can be eluted in a native or denatured state.

Features

  • High quality recombinant Protein A covalently bound to the particle surface
  • Ideal for IgG purification and immunoprecipitation
  • Minimum non-specific binding
  • Produced using a recombinant protein A fusion protein (~45 kDa), derived from E. coli fermentation
  • No aggregation
  • Efficiently automatable
  • Neutral optical properties

Applications

  • lgG purification
  • Immunoprecipitation
  • High yield protein purification
  • High yield antibody isolation

Contents

  • Magnetic Silica Beads coated with Protein A, 600nm, 1ml

Literature


Previously listed as catalog# PR-MAG00023-01