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Magnetofection magnetic transfection

AM70000 - AdenoMag Viral Gene Delivery Reagent (Adenovirus & Adeno Associated Virus)

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Starting at: $151.00

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AdenoMag is designed to be used in conjunction with adenoviruses and AAV:

MAIN FEATURES:

  • Optimized for adenoviruses and adeno associated viruse (AAV)
  • Suitable for all adenoviruses and AAV serotypes
  • Increase transduction efficiency (percentage of transduced cells and transgene expression)
  • Concentrate the entire viral dose on the cells very rapidly
  • Accelerate the transduction process
  • Infect non-permissive cells
  • Improve virus infectivity with very low vector doses
  • Synchronize cell adsorption/infection
  • Target/confine transduction to a specific area (magnetic targeting)
  • Universal (primary cells, hard-to-transfect cells, cell lines, non-permissive cells)
  • Serum compatible and non-toxic
  • No molecular biology or biochemical modifications required
  • Simple, rapid and ready-to use

AdenoMag utilizes Magnetofection technology to concentrate viral vectors on the target cells. This new technology exploits magnetic force exerted upon viral vectors associated with magnetic particles to drive the virus towards the target cells. In this manner the complete viral dose gets concentrated on the cells within a few minutes so that 100% of cells get in contact with a significant vector dose.

RL

 

The use of AdenoMag allows a significant improvement of percentage of infected cells and of gene expression compared with standard infection.

Adenovirus transduction efficiency

AdenoMag (GFP) increases infection in different cells

adenos 1

AdenoMag (LacZ) increases level of viral transgene expression

Adeno 2

 

Infection of non-permissive, hard-to-infect cells

Adenovirus infection of various cells

3a

Concentrate viruses and accelerate the infection process

Accelerate the kinetics of infectivity

Adeno 4

More AdenoMag Results

AdenoMag Instruction Manual

Magnetofection FAQ

Ordering information
100μl of AdenoMag reagent is sufficient for 500-1000 transfections in a 96-well plate. NOTE: As for all Magnetofection reagents, AdenoMag requires an appropriate magnetic field. Two magnetic plates especially designed for Magnetofection are provided to exert this specific magnetic field. The special geometry of one magnetic plate produces a strong magnetic field that is suitable for 96-well plates (cat. # MF10096) and the other one (cat. # MF-10000) is suitable for all culture dishes.