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Magnetofection magnetic transfection

AB00000 - AdenoBlast

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AdenoBlast

AdenoBlast is ideal to enhance adenoviral infection and transduction in any type of cells, adherent or in suspension, primary or cell lines. The use of adenoviral transduction requires the Coxsackie Adenovirus Receptor (CAR) for its initiation. Many cells express only low amounts of CAR making limited adenovirus-mediated transduction. AdenoBlast is based on an adenovirus binding peptide that assists transduction by coupling the adenoviral particles to the cell membrane in a CAR independent manner. Therefore adenoviral transduction is now possible even in non-permissive cells. AdenoBlast is non-toxic. 

Note: AdenoBlast is especially recommended when high multiplicities of infection (MOI) are used)

AdenoBlast benefits:
  • Enhances infection and transduction efficiency of adenovirus
  • Ideal for permissive and non-permissive cells
  • Non-toxic (potential for in vivo applications)
  • Compatible with cell lines and primary cells
  • Allows using reduced amounts of Adenovirus (low MOI), reducing the cost
Storage: +4°C
Shipping Conditions: Room Temperature
Recommended Applications: Increasing adenoviruses' transduction efficiency in any type of cells (adherent, suspension, primary, or cell lines) and transduction of non permissive / CAR-deficient cells